Publication in Coordination Chemistry Reviews

We offer a comprehensive overview of anticancer active platinum iodido complexes, together with the most relevant aspects of their mechanisms of action. We focused on all the structural types, differing in the platinum oxidation state, nuclearity, number of iodido ligands and type/s of donor atoms of the non-iodido ligands involved in the inner coordination sphere. The reviewed platinum iodido complexes offer such unique features that they might fuel the design of novel, highly active, more specific and safer potential platinum-based therapeutics.

Štarha, P.; Vančo, J.; Trávníček, Z. Platinum iodido complexes: A comprehensive overview of anticancer activity and mechanisms of action. Coordination Chemistry Reviews 2019, 380, 103–135. Link