Publication in European Journal of Medicinal Chemistry

Anticancer diiron aminocarbyne complexes with labile N-donor ligands

Authors: Sara Stocchetti, Ján Vančo, Giulio Bresciani, Lorenzo Biancalana, Jan Belza, Stefano Zacchini, Zdeněk Dvořák, Sara Benetti, Tarita Biver, Marco Bortoluzzi, Zdeněk Trávníček, Fabio Marchetti

Full-text: https://doi.org/10.1016/j.ejmech.2025.117304

Diiron(I) bis-carbonyl complexes incorporating various N-donors (acetonitrile, ammonia, primary amines) exhibited moderate to strong cytotoxicity against a panel of cancer cell lines, demonstrating distinct cellular effects compared to their tris-carbonyl precursors.